H. Begthel: search on Z-Library

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1

Oral mucosal organoids as a potential platform for personalized cancer therapy

Driehuis, Else, Kolders, Sigrid, Spelier, Sacha, Lohmussaar, Kadi, Willems, Stefan M, Devriese, Lot A., de Bree, Remco, de Ruiter, Emma J, Korving, Jeroen, Begthel, Harry, Van Es, Johan H, Geurts, Vee

Journal:

Cancer Discovery

Year:

2019

Language:

english

File:

PDF, 12.47 MB

english, 2019

2

Identification of stem cells in small intestine and colon by marker gene Lgr5

Barker, Nick, van Es, Johan H., Kuipers, Jeroen, Kujala, Pekka, van den Born, Maaike, Cozijnsen, Miranda, Haegebarth, Andrea, Korving, Jeroen, Begthel, Harry, Peters, Peter J.

Journal:

Year:

2007

Language:

english

File:

PDF, 3.74 MB

english, 2007

3

Assessing the origin of high-grade serous ovarian cancer using CRISPR-modification of mouse organoids

LÃµhmussaar, Kadi, Kopper, Oded, Korving, Jeroen, Begthel, Harry, Vreuls, Celien P. H., van Es, Johan H., Clevers, Hans

Journal:

Nature Communications

Year:

2020

File:

PDF, 2.53 MB

2020

4

Long-Term Expansion of Functional Mouse and Human Hepatocytes as 3D Organoids

Hu, Huili, Gehart, Helmuth, Artegiani, Benedetta, LÖpez-Iglesias, Carmen, Dekkers, Florijn, Basak, Onur, van Es, Johan, Chuva de Sousa Lopes, Susana M., Begthel, Harry, Korving, Jeroen, van den Born,

Journal:

Year:

2018

Language:

english

File:

PDF, 12.36 MB

english, 2018

5

In Vitro Expansion of Human Gastric Epithelial Stem Cells and Their Responses to Bacterial Infection

Bartfeld, Sina, Bayram, Tülay, van de Wetering, Marc, Huch, Meritxell, Begthel, Harry, Kujala, Pekka, Vries, Robert, Peters, Peter J., Clevers, Hans

Journal:

Gastroenterology

Year:

2015

Language:

english

File:

PDF, 4.78 MB

english, 2015

6

Identification of Multipotent Luminal Progenitor Cells in Human Prostate Organoid Cultures

Karthaus, Wouter R., Iaquinta, Phillip J., Drost, Jarno, Gracanin, Ana, van Boxtel, Ruben, Wongvipat, John, Dowling, Catherine M., Gao, Dong, Begthel, Harry, Sachs, Norman, Vries, Robert G.J., Cuppen,

Journal:

Year:

2014

Language:

english

File:

PDF, 3.94 MB

english, 2014

7

Notch/γ-secretase inhibition turns proliferative cells in intestinal crypts and adenomas into goblet cells

van Es, Johan H., van Gijn, Marielle E., Riccio, Orbicia, van den Born, Maaike, Vooijs, Marc, Begthel, Harry, Cozijnsen, Miranda, Robine, Sylvie, Winton, Doug J., Radtke, Freddy

Journal:

Year:

2005

Language:

english

File:

PDF, 407 KB

english, 2005

8

Mst4 and Ezrin Induce Brush Borders Downstream of the Lkb1/Strad/Mo25 Polarization Complex

Jean Paul ten Klooster, Marnix Jansen, Jin Yuan, Viola Oorschot, Harry Begthel, Valeria Di Giacomo, Frédéric Colland, John de Koning, Madelon M. Maurice, Peter Hornbeck, Hans Clevers

Journal:

Developmental Cell

Year:

2009

Language:

english

File:

PDF, 1.80 MB

english, 2009

9

Generation of an inducible colon-specific Cre enzyme mouse line for colon cancer research

Tetteh, Paul W., Kretzschmar, Kai, Begthel, Harry, van den Born, Maaike, Korving, Jeroen, Morsink, Folkert, Farin, Henner, van Es, Johan H., Offerhaus, G. Johan A., Clevers, Hans

Journal:

Proceedings of the National Academy of Sciences

Year:

2016

Language:

english

File:

PDF, 2.01 MB

english, 2016

10

Genetic dissection of colorectal cancer progression by orthotopic transplantation of engineered cancer organoids

Fumagalli, Arianna, Drost, Jarno, Suijkerbuijk, Saskia J. E., van Boxtel, Ruben, de Ligt, Joep, Offerhaus, G. Johan, Begthel, Harry, Beerling, Evelyne, Tan, Ee Hong, Sansom, Owen J., Cuppen, Edwin, Cl

Journal:

Proceedings of the National Academy of Sciences

Year:

2017

Language:

english

File:

PDF, 2.60 MB

english, 2017

11

A surgical orthotopic organoid transplantation approach in mice to visualize and study colorectal cancer progression

Fumagalli, Arianna, Suijkerbuijk, Saskia J E, Begthel, Harry, Beerling, Evelyne, Oost, Koen C, Snippert, Hugo J, van Rheenen, Jacco, Drost, Jarno

Journal:

Nature Protocols

Year:

2018

Language:

english

File:

PDF, 5.67 MB

english, 2018

12

Wnt signalling induces maturation of Paneth cells in intestinal crypts

van Es, Johan H., Jay, Philippe, Gregorieff, Alex, van Gijn, Marielle E., Jonkheer, Suzanne, Hatzis, Pantelis, Thiele, Andrea, van den Born, Maaike, Begthel, Harry, Brabletz, Thomas

Journal:

Nature Cell Biology

Year:

2005

Language:

english

File:

PDF, 1.23 MB

english, 2005

13

T-cell factor 4 (Tcf7l2) maintains proliferative compartments in zebrafish intestine

Muncan, Vanesa, Faro, Ana, Haramis, Anna-Pavlina G, Hurlstone, Adam F L, Wienholds, Erno, van Es, Johan, Korving, Jeroen, Begthel, Harry, Zivkovic, Danica, Clevers, Hans

Journal:

Year:

2007

Language:

english

File:

PDF, 485 KB

english, 2007

14

Generation and characterization of rat liver stem cell lines and their engraftment in a rat model of liver failure

Kuijk, Ewart W., Rasmussen, Shauna, Blokzijl, Francis, Huch, Meritxell, Gehart, Helmuth, Toonen, Pim, Begthel, Harry, Clevers, Hans, Geurts, Aron M., Cuppen, Edwin

Journal:

Scientific Reports

Year:

2016

Language:

english

File:

PDF, 2.13 MB

english, 2016

15

The Ets-Domain Transcription Factor Spdef Promotes Maturation of Goblet and Paneth Cells in the Intestinal Epithelium

Alex Gregorieff, Daniel E. Stange, Pekka Kujala, Harry Begthel, Maaike van den Born, Jeroen Korving, Peter J. Peters, Hans Clevers

Journal:

Gastroenterology

Year:

2009

Language:

english

File:

PDF, 5.07 MB

english, 2009

16

Adenomatous polyposis coli-deficient zebrafish are susceptible to digestive tract neoplasia

Haramis, Anna-Pavlina G, Hurlstone, Adam, van der Velden, Yme, Begthel, Harry, van den Born, Maaike, Offerhaus, G Johan A, Clevers, Hans C

Journal:

Year:

2006

Language:

english

File:

PDF, 402 KB

english, 2006

17

Expression Pattern of Wnt Signaling Components in the Adult Intestine

Alex Gregorieff, Daniel Pinto, Harry Begthel, Olivier Destrée, Menno Kielman, Hans Clevers

Journal:

Gastroenterology

Year:

2005

Language:

english

File:

PDF, 1.05 MB

english, 2005

18

Rapid Loss of Intestinal Crypts upon Conditional Deletion of the Wnt/Tcf-4 Target Gene c-Myc

Muncan, V., Sansom, O. J., Tertoolen, L., Phesse, T. J., Begthel, H., Sancho, E., Cole, A. M., Gregorieff, A., de Alboran, I. M., Clevers, H., Clarke, A. R.

Journal:

Molecular and Cellular Biology

Year:

2006

Language:

english

File:

PDF, 1.66 MB

english, 2006

19

Lipid-mediated Wnt protein stabilization enables serum-free culture of human organ stem cells

Tüysüz, Nesrin, van Bloois, Louis, van den Brink, Stieneke, Begthel, Harry, Verstegen, Monique M. A., Cruz, Luis J., Hui, Lijian, van der Laan, Luc J. W., de Jonge, Jeroen, Vries, Robert, Braakman, Er

Journal:

Nature Communications

Year:

2017

Language:

english

File:

PDF, 1.60 MB

english, 2017

20

MafB oncoprotein detected by immunohistochemistry as a highly sensitive and specific marker for the prognostic unfavorable t(14;20) (q32;q12) in multiple myeloma patients

Stralen, Ev, Leguit, R J, Begthel, H, Michaux, L, Buijs, A, Lemmens, H, Scheiff, J M, Doyen, C, Pierre, P, Forget, F

Journal:

Year:

2008

Language:

english

File:

PDF, 166 KB

english, 2008

21

Corrigendum: EphB receptor activity suppresses colorectal cancer progression

Batlle, Eduard, Bacani, Julinor, Begthel, Harry, Jonkheer, Suzanne, Gregorieff, Alexander, van de Born, Maaike, Malats, Núria, Sancho, Elena, Boon, Elles, Pawson, Tony

Journal:

Year:

2005

Language:

english

File:

PDF, 52 KB

english, 2005

22

ATP8B1-mediated spatial organization of Cdc42 signaling maintains singularity during enterocyte polarization

Bruurs, L. J. M., Donker, L., Zwakenberg, S., Zwartkruis, F. J., Begthel, H., Knisely, A. S., Posthuma, G., van de Graaf, S. F. J., Paulusma, C. C., Bos, J. L.

Journal:

The Journal of Cell Biology

Year:

2015

Language:

english

File:

PDF, 4.60 MB

english, 2015

23

An inducible mouse model for microvillus inclusion disease reveals a role for myosin Vb in apical and basolateral trafficking

K. Schneeberger, G. F. Vogel, H. Teunissen, D. D. Van Ommen, H. Begthel, L. El Bouazzaoui, A. H. M. Van Vugt, J. M. Beekman, J. Klumperman, T. Müller, A. Janecke, P. Gerner, L. A. Huber, M. W. Hess, H

Year:

2015

Language:

english

File:

PDF, 2.36 MB

english, 2015

24

Unlimited in vitro expansion of adult bi-potent pancreas progenitors through the Lgr5/R-spondin axis

Huch, Meritxell, Bonfanti, Paola, Boj, Sylvia F, Sato, Toshiro, Loomans, Cindy J M, van de Wetering, Marc, Sojoodi, Mozhdeh, Li, Vivian S W, Schuijers, Jurian, Gracanin, Ana, Ringnalda, Femke, Begthel

Journal:

The EMBO Journal

Year:

2013

Language:

english

File:

PDF, 4.02 MB

english, 2013

25

A Living Biobank of Breast Cancer Organoids Captures Disease Heterogeneity

Sachs, Norman, de Ligt, Joep, Kopper, Oded, Gogola, Ewa, Bounova, Gergana, Weeber, Fleur, Balgobind, Anjali Vanita, Wind, Karin, Gracanin, Ana, Begthel, Harry, Korving, Jeroen, van Boxtel, Ruben, Duar

Journal:

Year:

2017

Language:

english

File:

PDF, 8.61 MB

english, 2017

26

Patient-derived pancreatic tumour organoids identify therapeutic responses to oncolytic adenoviruses

Raimondi, Giulia, Mato-Berciano, Ana, Pascual-Sabater, Silvia, Rovira-Rigau, Maria, Cuatrecasas, Miriam, Fondevila, Constantino, SÃ¡nchez-CabÃºs, Santiago, Begthel, Harry, Boj, Sylvia F., Clevers, Han

Journal:

Year:

2020

File:

PDF, 5.89 MB

2020

27

EphB receptor activity suppresses colorectal cancer progression

Batlle, Eduard, Bacani, Julinor, Begthel, Harry, Jonkeer, Suzanne, Gregorieff, Alexander, van de Born, Maaike, Malats, Núria, Sancho, Elena, Boon, Elles, Pawson, Tony

Journal:

Year:

2005

Language:

english

File:

PDF, 446 KB

english, 2005

28

Prominin-1/CD133 Marks Stem Cells and Early Progenitors in Mouse Small Intestine

Hugo J. Snippert, Johan H. van Es, Maaike van den Born, Harry Begthel, Daniel E. Stange, Nick Barker, Hans Clevers

Journal:

Gastroenterology

Year:

2009

Language:

english

File:

PDF, 1.29 MB

english, 2009

29

The Leukemia-Associated Mllt10/Af10-Dot1l Are Tcf4/β-Catenin Coactivators Essential for Intestinal Homeostasis

Mahmoudi, Tokameh, Boj, Sylvia F., Hatzis, Pantelis, Li, Vivian S. W., Taouatas, Nadia, Vries, Robert G. J., Teunissen, Hans, Begthel, Harry, Korving, Jeroen, Mohammed, Shabaz, Heck, Albert J. R., Cle

Journal:

Year:

2010

Language:

english

File:

PDF, 2.64 MB

english, 2010

30

Lgr5+ve Stem Cells Drive Self-Renewal in the Stomach and Build Long-Lived Gastric Units In Vitro

Nick Barker, Meritxell Huch, Pekka Kujala, Marc van de Wetering, Hugo J. Snippert, Johan H. van Es, Toshiro Sato, Daniel E. Stange, Harry Begthel, Maaike van den Born, Esther Danenberg, Stieneke van d

Journal:

Year:

2010

Language:

english

File:

PDF, 3.38 MB

english, 2010

31

Lgr6 Marks Stem Cells in the Hair Follicle That Generate All Cell Lineages of the Skin

Snippert, H. J., Haegebarth, A., Kasper, M., Jaks, V., van Es, J. H., Barker, N., van de Wetering, M., van den Born, M., Begthel, H., Vries, R. G., Stange, D. E., Toftgard, R., Clevers, H.

Journal:

Year:

2010

Language:

english

File:

PDF, 719 KB

english, 2010

32

Sequential cancer mutations in cultured human intestinal stem cells

Drost, Jarno, van Jaarsveld, Richard H., Ponsioen, Bas, Zimberlin, Cheryl, van Boxtel, Ruben, Buijs, Arjan, Sachs, Norman, Overmeer, René M., Offerhaus, G. Johan, Begthel, Harry, Korving, Jeroen, van

Journal:

Year:

2015

Language:

english

File:

PDF, 6.83 MB

english, 2015

33

Reg4 + deep crypt secretory cells function as epithelial niche for Lgr5 + stem cells in colon

Sasaki, Nobuo, Sachs, Norman, Wiebrands, Kay, Ellenbroek, Saskia I. J., Fumagalli, Arianna, Lyubimova, Anna, Begthel, Harry, van den Born, Maaike, van Es, Johan H., Karthaus, Wouter R., Li, Vivian S.

Journal:

Proceedings of the National Academy of Sciences

Year:

2016

Language:

english

File:

PDF, 1.99 MB

english, 2016

34

Transcription Factor Achaete Scute-Like 2 Controls Intestinal Stem Cell Fate

Laurens G. van der Flier, Marielle E. van Gijn, Pantelis Hatzis, Pekka Kujala, Andrea Haegebarth, Daniel E. Stange, Harry Begthel, Maaike van den Born, Victor Guryev, Irma Oving, Johan H. van Es, Nick

Journal:

Year:

2009

Language:

english

File:

PDF, 2.77 MB

english, 2009

35

[BMJ Publishing Group Ltd ESGO Annual Meeting Abstracts - ()] Poster exhibition Day 2 - P119âAn organoid platform for ovarian cancer captures intra- and interpatient heterogeneity

Kopper, O, de Witte, CJ, LÃµhmussaar, K, Espejo Valle-Inclan, J, Hami, N, Kester, L, Balgobind, AV, Korving, J, Proost, N, Begthel, H, van Wijk, LM, Revilla, SA, Theeuwsen, R, van de Ven, M, van Roosm

File:

PDF, 68 KB

36

The Wnt/β-catenin pathway regulates cardiac valve formation

Hurlstone, Adam F. L., Haramis, Anna-Pavlina G., Wienholds, Erno, Begthel, Harry, Korving, Jeroen, van Eeden, Fredericus, Cuppen, Edwin, Zivkovic, Danica, Plasterk, Ronald H. A., Clevers, Hans

Journal:

Year:

2003

Language:

english

File:

PDF, 451 KB

english, 2003

37

Replacement of Lost Lgr5-Positive Stem Cells through Plasticity of Their Enterocyte-Lineage Daughters

Tetteh, Paul W., Basak, Onur, Farin, Henner F., Wiebrands, Kay, Kretzschmar, Kai, Begthel, Harry, van den Born, Maaike, Korving, Jeroen, de Sauvage, Frederic, van Es, Johan H., van Oudenaarden, Alexan

Journal:

Year:

2016

Language:

english

File:

PDF, 4.24 MB

english, 2016

38

Correction: The Leukemia-Associated Mllt10/Af10-Dot1l Are Tcf4/β-Catenin Coactivators Essential for Intestinal Homeostasis

Mahmoudi, Tokameh, Boj, Sylvia F., Hatzis, Pantelis, Li, Vivian S. W., Taouatas, Nadia, Vries, Robert G. J., Teunissen, Hans, Begthel, Harry, Korving, Jeroen, Mohammed, Shabaz, Heck, Albert J. R., Cle

Journal:

Year:

2017

Language:

english

File:

PDF, 1.35 MB

english, 2017

39

Correction for Muncan et al., “Rapid Loss of Intestinal Crypts upon Conditional Deletion of the Wnt/Tcf-4 Target Gene c- Myc ”

Muncan, Vanesa, Sansom, Owen J., Tertoolen, Leon, Phesse, Toby J., Begthel, Harry, Sancho, Elena, Cole, Alicia M., Gregorieff, Alex, Moreno de Alboran, Ignacio, Clevers, Hans, Clarke, Alan R.

Journal:

Molecular and Cellular Biology

Year:

2018

Language:

english

File:

PDF, 176 KB

english, 2018

40

Expression Pattern of Wnt Signaling Components in the Adult Intestine

GREGORIEFF, A, PINTO, D, BEGTHEL, H, DESTREE, O, KIELMAN, M, CLEVERS, H

Journal:

Gastroenterology

Year:

2005

Language:

english

File:

PDF, 1.05 MB

english, 2005

41

Crypt stem cells as the cells-of-origin of intestinal cancer

Barker, Nick, Ridgway, Rachel A., van Es, Johan H., van de Wetering, Marc, Begthel, Harry, van den Born, Maaike, Danenberg, Esther, Clarke, Alan R., Sansom, Owen J., Clevers, Hans

Journal:

Year:

2008

Language:

english

File:

PDF, 1.33 MB

english, 2008

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